282 research outputs found

    Generative Adversarial Networks Selection Approach for Extremely Imbalanced Fault Diagnosis of Reciprocating Machinery

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    At present, countless approaches to fault diagnosis in reciprocating machines have been proposed, all considering that the available machinery dataset is in equal proportions for all conditions. However, when the application is closer to reality, the problem of data imbalance is increasingly evident. In this paper, we propose a method for the creation of diagnoses that consider an extreme imbalance in the available data. Our approach first processes the vibration signals of the machine using a wavelet packet transform-based feature-extraction stage. Then, improved generative models are obtained with a dissimilarity-based model selection to artificially balance the dataset. Finally, a Random Forest classifier is created to address the diagnostic task. This methodology provides a considerable improvement with 99% of data imbalance over other approaches reported in the literature, showing performance similar to that obtained with a balanced set of data.National Natural Science Foundation of China, under Grant 51605406National Natural Science Foundation of China under Grant 7180104

    Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-β in colorectal cells.

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    Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors. However, studies of direct link between estrogen (especially estradiol E2), miRNA expression, and MMR in colorectal cancer (CRC) have not been done. In this study, we first evaluated the effects of estradiol (E2) and its antagonist ICI182,780 on the expression of miRNAs (miR-31, miR-155 and miR-135b) using COLO205, SW480 and MCF-7 cell lines, followed by examining the association of tissue miRNA expression and serum E2 levels using samples collected from 18 colorectal cancer patients. E2 inhibited the expressions of miRNAs in COLO205 cells, which could be reversed by E2 antagonist ICI 182.780. The expression of miR-135b was inversely correlated with serum E2 level and ER-β mRNA expression in CRC patients' cancer tissues. There were significant correlations between serum E2 level and expression of ER-β, miR-135b, and MMR in colon cancer tissue. This study suggests that the effects of estrogen on MMR function may be related to regulating miRNA expression via ER-β, which may be the basis for the anti-cancer effect in colorectal cells

    Dynamic analysis of buried steel pipeline subjected to blast seismic waves

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    A solution for dynamic stress concentration of buried pipeline with different material properties subjected to incident P waves is given by wave function expansion method. Through the quantitative analysis of the dynamic response of pipeline structures subjected to blasting seismic waves, the influence of the incident wave numbers, diameter-thick ratio and buried depth on dynamic stress concentration of both Q235 and X70 pipelines was revealed in the paper

    Intention-aware Long Horizon Trajectory Prediction of Surrounding Vehicles using Dual LSTM Networks

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    As autonomous vehicles (AVs) need to interact with other road users, it is of importance to comprehensively understand the dynamic traffic environment, especially the future possible trajectories of surrounding vehicles. This paper presents an algorithm for long-horizon trajectory prediction of surrounding vehicles using a dual long short term memory (LSTM) network, which is capable of effectively improving prediction accuracy in strongly interactive driving environments. In contrast to traditional approaches which require trajectory matching and manual feature selection, this method can automatically learn high-level spatial-temporal features of driver behaviors from naturalistic driving data through sequence learning. By employing two blocks of LSTMs, the proposed method feeds the sequential trajectory to the first LSTM for driver intention recognition as an intermediate indicator, which is immediately followed by a second LSTM for future trajectory prediction. Test results from real-world highway driving data show that the proposed method can, in comparison to state-of-art methods, output more accurate and reasonable estimate of different future trajectories over 5s time horizon with root mean square error (RMSE) for longitudinal and lateral prediction less than 5.77m and 0.49m, respectively.Comment: Published at the 21st International Conference on Intelligent Transportation Systems (ITSC), 201

    Programming hydrogel adhesion with engineered polymer network topology

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    Hydrogel adhesion that can be easily modulated in magnitude, space, and time is desirable in many emerging applications ranging from tissue engineering, and soft robotics, to wearable devices. In synthetic materials, these complex adhesion behaviors are often achieved individually with mechanisms and apparatus that are difficult to integrate. Here, we report a universal strategy to embody multifaceted adhesion programmability in synthetic hydrogels. By designing the surface network topology of a hydrogel, supramolecular linkages that result in contrasting adhesion behaviors are formed on the hydrogel interface. The incorporation of different topological linkages leads to dynamically tunable adhesion with high-resolution spatial programmability without alteration of bulk mechanics and chemistry. Further, the association of linkages enables stable and tunable adhesion kinetics that can be tailored to suit different applications. We rationalize the physics of chain slippage, rupture, and diffusion that underpins emergent programmable behaviors. We then incorporate the strategy into the designs of various devices such as smart wound patches, fluidic channels, drug-eluting devices, and reconfigurable soft robotics. Our study presents a simple and robust platform in which adhesion controllability in multiple aspects can be easily integrated into a single design of a hydrogel network

    Centrifuge experiment and numerical study on the dynamic response of air-backed plate to underwater explosion

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    This work compares experimental and numerical results concerning the elastic dynamic response of air-backed plate to underwater explosion. Experiments were performed in a centrifuge, both the shock loadings and structure responses were tested, and the bubble oscillation considering centrifugal force was predicted with Geer and Hunter model. The experimental and numerical results illustrates that the centrifugal force have no effect on shockwave for the short duration of action, and with the increase of centrifugal force, the bubble pulse motion cycle, maximum bubble radius, and peak pressure of bubble pulse decreased; both the peak of high-frequency and low-frequency response of the plate decline slightly when alpha damping rising ,the high-frequency response mode almost have no change with different alpha damping ,while, the low-frequency response tends to be an obvious oscillation waveform when the alpha damping is too low; although the difference of the peak acceleration owing to shock wave and bubble reaches to tens of times, the strain responses caused by the two factors are very close, which enucleates that the train response is related to shock energy and has a higher sensitivity to time accumulation; both the peak acceleration and peak strain due to the shock wave remain steady and the two kinds of response by bubble pulse decrease with the centrifugal force increasing; when the target position is more close to the area that the shock wave vertically impact ,the linear correlation between peak velocity and shock factor is much better. Key words: underwater explosion; centrifugal effect; FEM

    Perovskite quantum dot solar cells fabricated from recycled lead-acid battery waste

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    This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Materials Letters, copyright © 2021 American Chemical Societ, after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acsmaterialslett.1c00592.A cost-effective and environmentally friendly Pb source is a prerequisite for achieving large-scale, low-cost perovskite photovoltaic devices. Currently, the commonly used method to prepare the lead source is based on a fire smelting process, requiring a high temperature of more than 1000 °C, which results in environmental pollution. Spent car lead acid batteries are an environmentally hazardous waste; however, they can alternatively serve as an abundant and inexpensive Pb source. Due to “self-purification”, quantum dots feature a high tolerance of impurities in the precursor since the impurities tend to be expelled from the small crystalline cores during colloidal nucleation. Herein, PbI2 recycled from spent lead acid batteries via a facile low-temperature solution process is used to synthesize CsPbI3 quantum dots, which simultaneously brings multiple benefits including (1) avoiding pollution originating from the fire smelting process; (2) recycling the Pb waste from batteries; and (3) synthesizing high-quality quantum dots. The resulting CsPbI3 quantum dots have photophysical properties such as PLQY and carrier lifetimes on par with those synthesized from the commercial PbI2 due to expelling of the impurity Na atoms. The resulting solar cells deliver comparable power conversion efficiencies: 14.0% for the cells fabricated using recycled PbI2 and 14.7% for the cells constructed using commercial PbI2. This work paves a new and feasible path to applying recycled Pb sources in perovskite photovoltaics.Peer ReviewedPostprint (author's final draft

    CagA-positive Helicobacter pylori may promote and aggravate scrub typhus

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    Helicobacter pylori (H. pylori) infection may alter the host’s resistance to tsutsugamushi disease pathogens through the Th1 immune response, leading to potential synergistic pathogenic effects. A total of 117 scrub typhus cases at Beihai People’s Hospital and affiliated hospitals of Youjiang University for Nationalities and Medical Sciences were studied from January to December 2022, alongside 130 healthy individuals forming the control group. All participants underwent serum H. pylori antibody testing. The prevalence of H. pylori infection was significantly higher among scrub typhus patients (89.7%) compared to healthy individuals (54.6%) (p < 0.05). Moreover, type I H. pylori infection was notably more prevalent in scrub typhus cases (67.5%) compared to healthy individuals (30%) (p < 0.05). Multifactorial analysis demonstrated type I H. pylori infection as an independent risk factor for scrub typhus (adjusted odds ratio: 2.407, 95% confidence interval: 1.249–4.64, p = 0.009). Among scrub typhus patients with multiple organ damage, the prevalence of type I H. pylori infection was significantly higher (50.6%) than type II H. pylori infection (15.4%) (χ2 = 4.735, p = 0.030). These results highlight a higher incidence of H. pylori infection in scrub typhus patients compared to the healthy population. Additionally, type I H. pylori strain emerged as an independent risk factor for scrub typhus development. Moreover, individuals infected with type I H. pylori are more susceptible to multiple organ damage. These findings suggest a potential role of H. pylori carrying the CagA gene in promoting and exacerbating scrub typhus

    Search for the decay J/ψγ+invisibleJ/\psi\to\gamma + \rm {invisible}

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    We search for J/ψJ/\psi radiative decays into a weakly interacting neutral particle, namely an invisible particle, using the J/ψJ/\psi produced through the process ψ(3686)π+πJ/ψ\psi(3686)\to\pi^+\pi^-J/\psi in a data sample of (448.1±2.9)×106(448.1\pm2.9)\times 10^6 ψ(3686)\psi(3686) decays collected by the BESIII detector at BEPCII. No significant signal is observed. Using a modified frequentist method, upper limits on the branching fractions are set under different assumptions of invisible particle masses up to 1.2  GeV/c2\mathrm{\ Ge\kern -0.1em V}/c^2. The upper limit corresponding to an invisible particle with zero mass is 7.0×107\times 10^{-7} at the 90\% confidence level
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